导师简介
一、个人信息：
罗卓辉，博士，副研究员，硕士生导师
二、教育经历：
2015.09-2020.06 广州中医药大学，中药学，医学博士（硕博连读）
三、工作经历：
2020.12-2022.11 康芝药业股份有限公司/北京大学医学部 博士后
2022.12-至今 海南医科大学 副研究员
四、研究方向：
炎症与代谢性疾病药理研究。
五、科研项目：
1. 国家自然科学基金地区科学基金项目(82360882)，2024.01-2027.12，主持；
2. 海南省自然科学基金高层次人才项目(824RC522)，2024.03-2027.02，主持；
3. 海南省自然科学基金面上项目(826MS0156)，2026.03-2029.02，主持；
4. 中国博士后科学基金面上项目(2021M701026)，2021.09-2022.11，主持。
六、学术论文（#：第一作者，*：通讯作者）：
1. HY Hu#, KY Wang#, Y Qiu, ZB Xu, Y Chen, YJ Hu, JW Huang*, ZH Luo*. 3'-Hydroxypuerarin mitigates LPS-induced acute lung injury by inhibiting TLR4 activation-mediated NF-κB p65/NLRP3/GSDMD signaling. Front Immunol. 2026, 17, 1701778.
2. ZB Xu#, KY Wang#, XQ Wu, TT Chen, LK Xu, Y Qiu, HY Hu, Y Chen, JZ Cai*, YJ Hu*, JW Huang*, ZH Luo*. Cajanolactone A alleviates high-fat diet-induced MAFLD by modulating liver de novo lipogenesis, inflammatory signaling, and bile acid composition in the gut-liver axis. Biochem Pharmacol, 2026, 246, 117717.
3. ZB Xu#, KY Wang, HY Hu, Y Chen, Y Qiu, JZ Cai, WR Li, ZH Luo*, H Li*, JW Huang*. Protective effects of Exocarpium Citri Grandis against sepsis-induced acute lung injury via PANoptosis inhibition. Frontiers in Nutrition, 2025, 12, 1661404.
4. JB Chen#, XQ Wu, TT Chen, TQ Cui, DL Wu, M Qiu, QC Yi, ZY Zhang, CL Ma, Y Gao, YL Zhang*, ZH Luo*, JW Huang*. Ginsenoside Rg2 Ameliorates Metabolic Dysfunction-related Steatohepatitis via the Nrf2 Pathway by Suppressing Inflammation, Apoptosis, Oxidative Stress and Fibrosis. Phytomedicine, 2025, 149, 157552.
5. LK Xu#, WR Liu, XQ Wu, TT Chen, Y Gao*, JW Huang*, ZH Luo*. Citri Reticulatae Pericarpium improves obesity in OVX mice by regulating the gut microbiota and suppressing appetite. Food & Function, 2025, 16 (24), 9545-9561.
6. TT Chen#, XQ Wu, LK Xu, JX Zhao, WR Liu, JT Zeng*, ZH Luo*, JW Huang*. Exocarpium Citri Grandis alleviates postmenopausal obesity in ovariectomized mice through gut microbiota remodeling and metabolic reprogramming. Journal of Functional Foods, 2025, 135, 107102.
7. XQ Wu#, TT Chen, WR Liu, LK Xu, WM Ni, JW Huang*, ZH Luo*. Finger Citron Fruit counteracts ovariectomy-induced obesity through dual regulation of lipid metabolism and gut microbiota. Food Bioscience, 2025, 73, 107741.
8. KY Wang#, HY Hu#, ZB Xu, Y Chen, Y Qiu YJ Hu, JW Huang*, ZH Luo*. 7-Methoxyflavanone Alleviates LPS-Induced Acute Lung Injury by Suppressing TLR4/NF-κB p65 and ROS/Txnip/NLRP3 Signaling. Biology (Basel). 2025, 14 (9), 1170.
9. ZH Luo#, ZB Xu, KY Wang, HY Hu, JW Huang. Citri Sarcodactylis Fructus Alleviates LPS-Induced Acute Lung Injury by Inhibiting Inflammation and Inflammasome Activation. Food Science & Nutrition. 2025, 13, e70881.
10. JW Huang#, KL Zhou, JY Li, ZB Xu, XQ Wu, TT Chen, DN Wang, HF Pan, SQ Huang*, TW Liu*, ZH Luo*, Y Gao*. Poncirin ameliorates alcoholic liver injury by regulating lipid metabolism and inflammatory response in a PPARα dependent manner. Phytomedicine. 2025, 140, 156598.
11. QQ Meng#, ZP Li, XF He, YH Hu, GY Wu, JW Huang, ZH Luo*, YJ Hu*, XL Shen*. Anti-TNBC effects of Lappaol F by targeting epithelial-mesenchymal transition via regulation of GSK-3β-YAP-β-catenin and PI3K-AKT pathways. Front Pharmacol. 2025, 16, 1496511.
12. ZB Xu#, KY Wang, HY Hu, YJ Hu*, JW Huang,*, ZH Luo*. Sinensetin attenuates LPS-induced acute pulmonary inflammation in mice and RAW264.7 cells by modulating NF-κB p65-mediated immune resistance and STAT3-mediated tissue resilience. International Immunopharmacology. 2025, 148, 114101.
13. ZB Xu#, HY Hu, KY Wang, ZY Zhou, XQ He, XA Huang, YJ Hu*, JW Huang*, ZH Luo*. Sinensetin, a polymethoxyflavone from citrus fruits, ameliorates LPS-induced acute lung injury by suppressing Txnip/NLRP3/Caspase-1/GSDMD signaling-mediated inflammatory responses and pyroptosis. Food Funct. 2024, 15 (14), 7592-7604.
14. ZB Xu#, JY Li, KL Zhou, KY Wang, HY Hu, YJ Hu*, Y Gao*, ZH Luo*, JW Huang*. Exocarpium Citri Grandis ameliorates LPS-induced acute lung injury by suppressing inflammation, NLRP3 inflammasome, and ferroptosis. J Ethnopharmacol. 2024, 329, 118162.
15. JW Huang#, ZB Xu#, JY Li, XQ He, XA Huang, XL Shen*, ZH Luo*. Systems pharmacology-based dissection of potential mechanisms of Exocarpium Citri Grandis for the treatment of chronic bronchitis. Arab J Chem. 2024. 17 (1), 105428.
七、联系方式：
zhuohuiluo@muhn.edu.cn
