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个人简介
薛鹏，主任医师，教授，博士生导师。内科学博士，Johns Hopkins Medicine博士后。海南省医学科学院课题组长，海南医科大学第一附属医院内分泌科学科带头人。担任中华医学会骨质疏松和骨矿盐疾病学分会委员，中华医学会骨质疏松和骨矿盐疾病学分会代谢性骨病学组委员，中国医师协会内分泌代谢科医师分会骨代谢学组委员，《中华骨质疏松和骨矿盐疾病》杂志编委。
科研工作：主持和参与多项国家和省级课题。在国际重要学术刊物如Journal of Clinical Investigation和Bone Research等期刊上发表SCI收录论文30余篇。获省科技进步二等奖，省医学科技一等奖。
临床工作：擅长代谢性骨病、糖尿病及并发症、甲状腺疾病、血脂异常、痛风、肾上腺疾病、垂体疾病的诊断和治疗。2018年荣获 “CSOBMR ‘菁英杯’骨质疏松指南竞答暨病例分享大赛”冠军，2022年被授予“最美逆行者”称号。
研究方向
1. 骨骼肌肉代谢性疾病的发病机制和临床干预策略；
2. 脊柱退变导致腰痛的发生机制和临床干预靶点。
主要学习和工作经历
2025.09-至今，海南省医学科学院，课题组长
2025.09-至今，海南医科大学第一附属医院内分泌科，学科带头人
2022.12-2025.09，河北医科大学第三医院，主任医师，教授
2018.11-2021.03，Johns Hopkins Medicine博士后
2011.09-2014.07，河北医科大学，内科学博士
代表性论文
1. Peng Xue, Weixin Zhang, Mengxi Shen, Junhua Yang, Jiachen Chu, Shenyu Wang, Mei Wan, Junying Zheng, Zhaozhu Qiu, Xu Cao. Proton-Activated Chloride Channel Increases Endplate Porosity and Pain in a Mouse Spinal Degeneration Model. J Clin Invest. 2024, 134(20): e168155. （IF=13.600，第一作者）
2. Peng Xue, Shenyu Wang, Xiao Lyu, Mei Wan, Xialin Li, Lei Ma, Neil C Ford, Yukun Li, Yun Guan, Wenyuan Ding, Xu Cao. PGE2/EP4 skeleton interoception activity reduces vertebral endplate porosity and spinal pain with low-dose celecoxib. Bone Res. 2021, 9(1): 1-36. （IF=13.362，第一作者）
3. Na Wang, Zhe Lin, Liu Gao, Bin Wang, Kangxu Wei, Menghan Zhang, Yukun Li, Peng Xue. Liraglutide reduces bone marrow adipogenesis by miR-150-5p/ GDF11 axis in diabetic rats. Eur J Pharmacol, 2024, 978: 176793. （IF=4.200，通讯作者）
4. Liu Gao, Chang Liu, Pan Hu, Na Wang, Xiaoxue Bao, Bin Wang, Ke Wang, Yukun Li, Peng Xue. The role of advanced glycation end products in fracture risk assessment in postmenopausal type 2 diabetic patients. Front Endocrinol, 2022; 13: 1-11. (IF=6.055，通讯作者)
5. Ziyi Li, Chang Liu, Xiaoli Liu, Na Wang, Liu Gao, Xiaoxue Bao, Sijing Liu, Peng Xue. Aucubin Impeded Preosteoclast Fusion and Enhanced CD31(hi) EMCNhi Vessel Angiogenesis in Ovariectomized Mice. Stem Cells Int, 2022, 2022: 1-19. (IF=5.131，通讯作者)
6. Na Wang, Ziyi Li, Shilun Li, Yukun Li, Liu Gao, Xiaoxue Bao, Ke Wang, Chang Liu, Peng Xue, Sijing Liu. Curculigoside Ameliorates Bone Loss by Influencing Mesenchymal Stem Cell Fate in Aging Mice. Front Cell Dev Biol, 2021, 9: 767006. (IF=6.081，通讯作者)
7. Ziyi Li, Chang Liu, Shilun Li, Ting Li, Yukun Li, Na Wang, Xiaoxue Bao, Peng Xue, Sijing Liu. BMSC-Derived Exosomes Inhibit Dexamethasone-Induced Muscle Atrophy via the miR-486-5p/FoxO1 Axis. Front Endocrinol, 2021, 12:681267. (IF=6.055，通讯作者)
8. Sijing Liu, Qiong Wang, Ziyi Li, Lei Ma, Ting Li, Yukun Li, Na Wang, Chang Liu, Peng Xue, Chuan Wang. TRPV1 Channel Activated by the PGE2/EP4 Pathway Mediates Spinal Hypersensitivity in a Mouse Model of Vertebral Endplate Degeneration. Oxid Med Cell Longev, 2021, 2021: 1-16. (IF=7.31，通讯作者)
9. Na Wang, Yukun Li, Sijing Liu, Liu Gao, Chang Liu, Xiaoxue Bao, Peng Xue. Bioinformatics Analysis and Validation of Differentially Expressed MicroRNAs with their Target Genes Involved in GLP-1RA Facilitated Osteogenesis. Curr Bioinform, 2021, 16: 1-15. (IF=4.85，通讯作者)
10. Na Wang, Yukun Li, Ziyi Li, Chang Liu, Peng Xue. Sal B targets TAZ to facilitate osteogenesis and reduce adipogenesis through MEK-ERK pathway. J Cell Mol Med, 2019, 23(5): 3683-3695. (IF=4.486，通讯作者)
11. Na Wang, Yukun Li, Ziyi Li, Jianxia Ma, Xuelun Wu, Runzhou Pan, Yan Wang, Liu Gao, Xiaoxue Bao, Peng Xue. IRS-1 targets TAZ to inhibit adipogenesis of rat bone marrow mesenchymal stem cells through PI3K-Akt and MEK-ERK pathways. Eur J Pharmacol, 2019, 849(4): 11-21. (IF=3.263，通讯作者)
